It is all based on the type of connection you have available on your motherboard for the video card that determines that possibility. Most of the times if you have a PCI Express slot open and/or available, then you will be able to mount an HDMI-ready video card. Just keep in mind that if your specs on the motherboard read PCI Express x16 and you have two slots for video cards open, it will probably put the output of the buses at x8 per video card slot. Very few motherboards, without having to pay for the features, will feature true x16 or even in the extreme cases and HIGH dollar cases, x24 output. Just check in your manual or online to see what the specs on your motherboard are and then determine it from that and what I just told/wrote you. Good luck with your installation. Let us know if you have any further questions.