if you are using windows vista.

You should have quick start icons right beside your start menu button.

Hit:
windows key + 1 to start the first one
windows key + 2 to start the second one
windows key + 3 to start the third one
...etc.


also.

Hit Ctrl + Shift + Esc to bring up the task manager.
(can do it with one hand)
Alternate to Ctrl + Alt + Del.