my top places in the south:
New Orleans - always a classic and from what i was told the tourist areas are back open and really where affected (french quarter)... if you go down check out
www.loft523.com nice hip hotel
Savannah - little taste of new orleans, small, but lots of pubs/entertainment to enjoy, closest place to get some good sea food + get to watch the ship port stay at golf/spa resort across the water (westin or hyatt

)
Gatlinburg - its beautiful drive through the mountains that time of year and you have red neck disney world next door Pigeon Forge w/ all the games you can think of. just rent a cabin, walk the shops, take the sky lift, etc...
Tampa - nice city much like atlanta with tons of shit to do. they have tons of clubs, shows, events, etc... Yobor(sp?) is a small part of downtown like our Atlantic Station has basically indoor/outdoor mall. beach is close; one of my favorite attractions is the Dali Museum St. Pete which i guess is a 20min drive from downtown Tampa.
Chattanooga - actually has some nice shit to check out. Aquarium is cool. They have a old train station that was converted into a hotel downtown. You can stay in the actually rail cars

There is also a tons of shit in that downtown area, shops, Imax, museums, etc..
other options: Grove Park in NC (spa/golf resort), Biltmore Mansion, Nashville pretty cool town, etc...