The Bible says your body is the temple of God. Simply put, why would you purposefully destroy God's dwelling place with anything? Can a foggy mind or destroyed brain cells lead to anything good? We are stewards pf the things God has Created and given us, including our bodies. All will answer for their stewardship. With regard to alchohol the Bible says "Wine is a mocker, strong drink is raging: and whosoever is deceived thereby is not wise".