ozzy's physical and mental degraded state was caused by years of alchohol abuse and hard drugs.Originally Posted by YokotaS13
It is generally considered to be impossible to achieve a lethal overdose by smoking cannabis. According to the Merck Index, 12th edition, the LD50, the lethal dose for 50% of rats tested by inhalation, is 42 mg/kg of body weight. That is equivalent of a 165 lb (75 kg) man ingesting all of the THC in 21 one-gram cigarettes of high-potency (15% THC) cannabis buds at once, assuming no THC was lost through burning or exhalation. For oral consumption, the LD50 for rats is 1270 mg/kg and 730 mg/kg for males and females, respectively, equivalent to the THC in about a pound of 15% THC cannabis. Only with intravenous administration — an unheard-of method of use — may such a level be even theoretically possible.
There has only ever been one(1) recorded verdict (although not ultimately upheld) of fatal overdose due to cannabis. In January 2004, Lee Maisey of Pembrokeshire, Wales was found dead. The coroner's report stated "Death due to probable cannabis toxicity". It had been reported that Maisey smoked about six joints a day. Mr. Maisey's blood contained 130 nanograms per milliliter (ng/ml) of the THC metabolite THC-COOH. However, the validity of the finding did not stand up well under review. As reported on 2004-01-28 in the Neue Züricher Zeitung, the Federal Health Ministry of Switzerland asked Dr. Rudolf Brenneisen, a professor at the department for clinical research at the University of Bern, to review the data of this case. Dr. Brenneisen said that the data of the toxicological analysis and collected by autopsy were "scanty and not conclusive" and that the conclusion "death by cannabis intoxication" was "not legitimate."
NOTES. it is physically impossible to over dose from weed, a 165 pound guy would have to eat an entire pound of weed to die. also there has only ever been one report of death by weed and it was not legitimate.
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