^^^ The effects are called "after-effects" for a reason. On average, it usually takes about 24-48 hours for any paralysis to take affect. If it does. You will notice it happening if, when you go to bed, you wake up feeling tired, you have stuff in the corners of your eyes, and you have a wet spot on your pillow from drooling because you couldn't feel the drool coming out so you could suck it back in. Later, QD.