It only took one good cut to make me start wearing gloves. Now I have gone through 4-5 pairs of them (worn holes in them). I won't do any major wrenching without them. Obviously some things you can't do with the gloves one (soldering, or trying to thread bolts in tight places, etc), but for everything else, yeah, I'll wear them.

Right now I'm a professional bassist, so if my hands get screwed up, I can't do my job. (I've tried playing bass with open wounds....bloody strings slow me down).