The Anti seize probably didn't help, it tends to make your torque readings wrong. Typically there's not a lot of metal on metal interaction between studs and lugs, but it is possible depending on the composition of your wheels, studs and nuts. Depending on what kind of car you have though, some of your problems might be from old studs. Hondas are well known for having issues with non-oem lugnuts coming loose unless over-torqued. The over-torquing on the honda studs then causes them to distort their shape (They get longer and the threads lean over towards the outside) which eventually causes them to either stress-fracture and snap or seize up because the threads aren't straight and even.