Everyone is saying something different because you really haven't given any information. If it was running fine and now that you changed the plug wires and its not running on one cylinder even with the old wires then you need to check the terminal on the cap and also make sure the old plug end didn't get stuck on the plug when you pulled the wire off. I doubt the wires are to blame since the old ones don't work either. Its either something you did or there is a problem with the #2 terminal on the cap or the plug end like I mentioned before.