A lot of misinformation in this thread. As someone else said any bike from the big 4 will last 100,000 miles maintained properly. I would not have a problem buying a bike with 20K miles that was taken care of, vs a bike with 2K that's been stunted or wrecked a couple times. There's a guy on www.georgiasportbike.com with a CBR that has over 100K on it, and he hasn't had to do anything but change the oil, tires, air filter, and chain. It still looks better than a lot of bikes that are 2 yrs old. Because he takes care of it. Inline 4 motorcycle engines are not far from a 4cyl car engine. Just smaller in displacement.
Most bikes don't make it that far because they get wrecked first, and with frames that are so vulnerable, all it takes is 1 scratch on the frame to total a bike. Even if you ride defensively, odds are someone else in a car will take you out before you ever reach 100K miles. It's pretty hard to reach that mileage unless you ride every day, and have a long commute. The guy I mentioned above rode it over 100 miles a day. When it was raining, and when it was 20 degrees. And then he rides on the weekends.