CROME is a cheap way to tune your car, but it requires an OBD-1 ECU. For OBD-0 I would recommend TurboEdit, or if you can find one cheap, Zdyne. No matter what ECU or program you go with, you must have it tuned for your setup, preferably on a dyno. Zdyne can do anything, but for a B16 you will otherwise need an OBD-0 ECU with an output for VTEC. This basically limits you to a chipped PR3, PW0, or PS9.

Don't go with Hondata, not only because they are overpriced, but because of their recent lawsuits against the tuning community. They're ripping off their own userbase, so **** them.