My dohc F20a (basically a nonvtec F20b) is making 202whp at 6psi. it should make close to 300whp at 12psi.

Take into consideration your supporting mods (Mine is stock, besides the 550cc injectors), A bit higher compression (I'm at 9.5:1) and Vtec (probably adds 15ish hp, just a guess)

You should be completely fine at 10-12 psi, but I'd get a reliable wideband, turn up the boost to 6psi, watch AFR, 8psi, watch AFR, 10psi, 12psi. If you're leaning out too much, add more fuel. And as always, get a good tune.