If you were running 15:1 compression and didnt want to run Race gas, then yea i could see a benefit.

All Meth is, is a substitute for race gas and its MUCH more corrosive and damaging. Race gas you might lose an 02 sensor every once in awhile. Meth will eat any aluminum including fuel lines, bearings, all kinds of vital engine parts and components.

Using meth doesnt ADD power, if allows you to have a more aggressive tune without the octane additive if that makes sense.

So no, its pointless IMO , you are better off putting C16 in it than Meth