If you can fit 225/50/16 I wouldn't give that so much as a second thought.
A LOT of variety and some great (and reasonably priced) performance based choices in that size. It's about 18mm more overall diameter, but decreases sidewall by about 16.5mm, which is nice for decreasing tire roll in cornering (not to mention the extra 10mm of tire on the road ).
I'm all about functionality.